Human NIPSNAP1 Recombinant Protein (RPPB4098)
- SKU:
- RPPB4098
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- NIPSNAP1
- Synonyms:
- Nipsnap Homolog 1 (C Elegans)
- 4 Nitrophenylphosphatase Domain And Non-Neuronal SNAP25-Like 1
- NIPSNAP
- C Elegans
- Source:
- Escherichia Coli
- Uniprot:
- Q9BPW8
Description
| Product Name: | Human NIPSNAP1 Recombinant Protein |
| Product Code: | RPPB4098 |
| Size: | 20µg |
| Species: | Human |
| Target: | NIPSNAP1 |
| Synonyms: | Nipsnap Homolog 1 (C. Elegans), 4 Nitrophenylphosphatase Domain And Non-Neuronal SNAP25-Like 1, NIPSNAP, C. Elegans, Homolog, Protein NipSnap Homolog 1, NipSnap1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | NIPSNAP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAPRLCS ISVTARRLLG GPGPRAGDVA SAAAARFYSK DNEGSWFRSL FVHKVDPRKD AHSTLLSKKE TSNLYKIQFH NVKPEYLDAY NSLTEAVLPK LHLDEDYPCS LVGNWNTWYG EQDQAVHLWR FSGGYPALMD CMNKLKNNKE YLEFRRERSQMLLSRRNQLL LEFSFWNEPQ PRMGPNIYEL RTYKLKPGTM IEWGNNWARA IKYRQENQEA VGGFFSQIGE LYVVHHLWAY KDLQSREETR NAAWRKRGWD ENVYYTVPLV RHMESRIMIP LKISPLQ |
NipsnapHomolog 1 (NIPSNAP1) belongs to the NipSnap family. NIPSNAP1 may take part invesicular transport. A similar protein in mice inhibits the calciumchannel TRPV6, and it is localized to the inner mitochondrial membraneas well, where it may be involved in mitochondrial DNA maintenance. Apseudogene of NIPSNAP1 is located on the short arm ofchromosome 17. Among the diseases associated with NIPSNAP1 are maple syrupurine disease, and phenylketonuria.
NIPSNAP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 307 amino acids (1-284a.a) and having a molecular mass of 35.7kDa.NIPSNAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NIPSNAP1: a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] |
| UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: mitochondrion; mitochondrial inner membrane Molecular Function:neurotransmitter binding Biological Process: sensory perception of pain |
| NCBI Summary: | This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] |
| UniProt Code: | Q9BPW8 |
| NCBI GenInfo Identifier: | 193211616 |
| NCBI Gene ID: | 8508 |
| NCBI Accession: | NP_003625 |
| UniProt Secondary Accession: | Q9BPW8,O43800, B2RAY3, |
| UniProt Related Accession: | Q9BPW8 |
| Molecular Weight: | 33,310 Da |
| NCBI Full Name: | protein NipSnap homolog 1 isoform 1 |
| NCBI Synonym Full Names: | nipsnap homolog 1 (C. elegans) |
| NCBI Official Symbol: | NIPSNAP1 |
| NCBI Protein Information: | protein NipSnap homolog 1 |
| UniProt Protein Name: | Protein NipSnap homolog 1 |
| Protein Family: | Protein |
| UniProt Gene Name: | NIPSNAP1 |
| UniProt Entry Name: | NIPS1_HUMAN |
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