Human NDUFA5 Recombinant Protein (RPPB2005)
- SKU:
- RPPB2005
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- NDUFA5
- Synonyms:
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
- Complex I subunit B13
- Complex I-13kD-B
- CI-13kD-B
- Source:
- Escherichia Coli
- Uniprot:
- Q16718
Description
| Product Name: | Human NDUFA5 Recombinant Protein |
| Product Code: | RPPB2005 |
| Size: | 10µg |
| Species: | Human |
| Target: | NDUFA5 |
| Synonyms: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, Complex I subunit B13, Complex I-13kD-B, CI-13kD-B, NADH-ubiquinone oxidoreductase 13 kDa-B subunit, NDUFA5, B13, NUFM, UQOR13, CI-13kB. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The NDUFA5 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAGVLKK TTGLVGLAVC NTPHERLRIL YTKILDVLEE IPKNAAYRKY TEQITNEKLA MVKAEPDVKK LEDQLQGGQL EEVILQAEHE LNLARKMREW KLWEPLVEEP PADQWKWPI |
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (NDUFA5) is a member of the complex I NDUFA5 subunit family. The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain that transfers electrons from NADH to ubiquinone. The NDUFA5 protein localizes to the inner mitochondrial membrane as part of the seven component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, even though its exact role is undetermined.
NDUFA5 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (1-116) and having a molecular mass of 15.8kDa.NDUFA5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NDUFA5: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA5 subunit family. |
| UniProt Protein Details: | Protein type:EC 1.6.5.3; Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; EC 1.6.99.3 Chromosomal Location of Human Ortholog: 7q31.33 Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I Molecular Function:NADH dehydrogenase (ubiquinone) activity Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone |
| NCBI Summary: | This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014] |
| UniProt Code: | Q16718 |
| NCBI GenInfo Identifier: | 2499316 |
| NCBI Gene ID: | 4698 |
| NCBI Accession: | Q16718.3 |
| UniProt Related Accession: | Q16718 |
| Molecular Weight: | |
| NCBI Full Name: | NADH dehydrogenase |
| NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase subunit A5 |
| NCBI Official Symbol: | NDUFA5 |
| NCBI Official Synonym Symbols: | B13; NUFM; UQOR13; CI-13kB; CI-13KD-B |
| NCBI Protein Information: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 |
| UniProt Protein Name: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 |
| UniProt Synonym Protein Names: | Complex I subunit B13; Complex I-13kD-B; CI-13kD-B; NADH-ubiquinone oxidoreductase 13 kDa-B subunit |
| UniProt Gene Name: | NDUFA5 |
| UniProt Entry Name: | NDUA5_HUMAN |
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