Human MIEN1 Recombinant Protein (RPPB3974)
- SKU:
- RPPB3974
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- MIEN1
- Synonyms:
- C17orf37
- C35
- ORB3
- RDX12
- Source:
- Escherichia Coli
- Uniprot:
- Q9BRT3
Description
| Product Name: | Human MIEN1 Recombinant Protein |
| Product Code: | RPPB3974 |
| Size: | 20µg |
| Species: | Human |
| Target: | MIEN1 |
| Synonyms: | C17orf37, C35, ORB3, RDX12, XTP4, HBV X-transactivated gene 4 protein, HBV XAg-transactivated protein 4, Protein C35, Migration and invasion enhancer 1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | MIEN1 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSGEPGQ TSVAPPPEEV EPGSGVRIVV EYCEPCGFEA TYLELASAVK EQYPGIEIES RLGGTGAFEI EINGQLVFSK LENGGFPYEK DLIEAIRRAS NGETLEKITN SRPPC |
Migration And Invasion Enhancer 1 (MIEN1) is a member of the SelWTH family. MIEN1 enhances cell migration by stimulating filopodia formation at the leading edge of migrating cells and takes parts in regulation of apoptosis, probably via control of CASP3. MIEN1 participates in a redox-related process as well.
MIEN1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 135 amino acids (1-112 a.a.) and having a molecular mass of 14.5kDa.MIEN1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MIEN1: Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. Belongs to the SelWTH family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q12 Cellular Component: cytoplasm; cytosol; nucleoplasm Molecular Function:protein binding Biological Process: apoptosis; negative regulation of apoptosis; positive regulation of cell migration; positive regulation of filopodium formation |
| UniProt Code: | Q9BRT3 |
| NCBI GenInfo Identifier: | 29468235 |
| NCBI Gene ID: | |
| NCBI Accession: | AF490253.1 |
| Molecular Weight: | 12,403 Da |
| NCBI Full Name: | Homo sapiens XTP4 (XTP4) mRNA, complete cds |
| UniProt Protein Name: | Migration and invasion enhancer 1 |
| UniProt Synonym Protein Names: | HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; Protein C35 |
| UniProt Gene Name: | MIEN1 |
| UniProt Entry Name: | MIEN1_HUMAN |
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