Description
| Product Name: | Human GMFG Recombinant Protein |
| Product Code: | RPPB0366 |
| Size: | 20µg |
| Species: | Human |
| Target: | GMFG |
| Synonyms: | Glia maturation factor gamma, GMF-gamma, GMFG, MGC126867. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless clear solution. |
| Formulation: | The GMF-gamma protein contains 20mM Tris-HCl pH-8, 1mM DTT, 1mM EDTA and 10% Glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MSDSLVVCEV DPELTEKLRK FRFRKETDNA AIIMKVDKDR QMVVLEEEFQ NISPEELKME LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQQMMYAGSKNR LVQTAELTKV FEIRTTDDLT EAWLQEKLSF FR |
GMFG is a hematopoietic-specific protein that mediates the pluripotentiality and lineage commitment of human hematopoietic stem cells. Glia maturation factor gamma is a cytokine-responsive protein in EPO-induced and G-CSF-induced hematopoietic lineage development. Glia maturation factor also acts as a Nerve Growth Factor in nervous system development, angiogenesis and immune function. GMFG possesses hematopoietic tissue-specific gene expression, a promoter concentrated with high-score hematopoiesis-specific transcription factors, and molecular coevolution with a rudimentary blood/immune system.
Glia Maturation Factor-Gamma (GMF-Gamma) Human Recombinant produced in E.Coli is a signle, non-glycosylated, polypeptide chain containing 142 amino acids and having a total molecular mass of 16.8 kDa. Glia Maturation Factor-Gamma, GMF-Gamma, Human Recombinant is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | GMF-gamma: Belongs to the actin-binding proteins ADF family. GMF subfamily. |
| UniProt Protein Details: | Protein type:Actin-binding Chromosomal Location of Human Ortholog: 19q13.2 Molecular Function:enzyme activator activity; protein kinase inhibitor activity Biological Process: protein amino acid phosphorylation |
| UniProt Code: | O60234 |
| NCBI GenInfo Identifier: | 6831548 |
| NCBI Gene ID: | 9535 |
| NCBI Accession: | O60234.1 |
| UniProt Secondary Accession: | O60234,Q6IB37, |
| UniProt Related Accession: | O60234 |
| Molecular Weight: | 16,801 Da |
| NCBI Full Name: | Glia maturation factor gamma |
| NCBI Synonym Full Names: | glia maturation factor gamma |
| NCBI Official Symbol: | GMFG�� |
| NCBI Official Synonym Symbols: | GMF-GAMMA�� |
| NCBI Protein Information: | glia maturation factor gamma |
| UniProt Protein Name: | Glia maturation factor gamma |
| Protein Family: | Glia maturation factor |
| UniProt Gene Name: | GMFG�� |
| UniProt Entry Name: | GMFG_HUMAN |
