Description
| Product Name: | Human DBNDD2 Recombinant Protein |
| Product Code: | RPPB3330 |
| Size: | 10µg |
| Species: | Human |
| Target: | DBNDD2 |
| Synonyms: | Dysbindin domain-containing protein 2, Casein kinase-1 binding protein, CK1BP, HSMNP1, DBNDD2, C20orf35. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | DBNDD2 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMDPNPR AALERQQLRL RERQKFFEDI LQPETEFVFP LSHLHLESQR PPIGSISSME VNVDTLEQVE LIDLGDPDAA DVFLPCEDPP PTPQSSGMDN HLEELSLPVP TSDRTTSRTS SSSSSDSSTN LHSPNPSDDG ADTPLAQSDE EEERGDGGAE PGACS |
Dysbindin domain-containing protein 2 (DBNDD2) is a member of the dysbindin family. DBNDD2 regulates the activity of casein kinase-1 and inhibits CSNK1D autophosphorylation (in vitro). DBNDD2 also interacts with CSNK1D and CSNK1E. DBNDD2 is detected in brain.
DBNDD2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids (1-161 a.a) and having a molecular mass of 20.1kDa (Molecular weight on SDS-PAGE will appear higher).DBNDD2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | DBNDD2: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro). Belongs to the dysbindin family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 20q13.12Cellular Component: synaptic vesicle membraneMolecular Function: protein bindingBiological Process: negative regulation of protein kinase activity; neurite development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9BQY9 |
| NCBI GenInfo Identifier: | 115299745 |
| NCBI Gene ID: | 55861 |
| NCBI Accession: | NP_001041686.1 |
| UniProt Secondary Accession: | Q9BQY9,Q331S6, Q5QPV4, Q5QPV6, Q9BQZ0, Q9BVL1, Q9H1F6 Q9NWZ0, Q9NY07, Q9NZ31 |
| UniProt Related Accession: | Q9BQY9 |
| Molecular Weight: | 33.48kD |
| NCBI Full Name: | dysbindin domain-containing protein 2 isoform a |
| NCBI Synonym Full Names: | dysbindin domain containing 2 |
| NCBI Official Symbol: | DBNDD2�� |
| NCBI Official Synonym Symbols: | CK1BP; HSMNP1; C20orf35�� |
| NCBI Protein Information: | dysbindin domain-containing protein 2 |
| UniProt Protein Name: | Dysbindin domain-containing protein 2 |
| UniProt Synonym Protein Names: | Casein kinase-1 binding protein; CK1BP; HSMNP1 |
| Protein Family: | Dysbindin domain-containing protein |
| UniProt Gene Name: | DBNDD2�� |
| UniProt Entry Name: |
