Description
| Product Name: | Human CTRB1 Recombinant Protein |
| Product Code: | RPPB1511 |
| Size: | 10mg |
| Species: | Human |
| Target: | CTRB1 |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered lyophilized powder. |
| Formulation: | The Human CTRB1 was lyophilized without any additives. |
| Solubility: | It is recommended to reconstitute the lyophilized Human CTRB1 in 1ml 50mM HAc which can then be further diluted to other aqueous solutions. |
| Stability: | Recombinant Human CTRB1 although stable at room temp for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95% asdetermined by HPLC. |
| Amino Acid Sequence: | CG VPAIHPVLSG LSRIVNGEDA VPGSWPWQVS LQDKTGFHFC GGSLISEDWVVTAAHCGVRT SDVVVAGEFD QGSDEENIQV LKIAKVFKNP KFSILTVNND ITLLKLATPA RFSQTVSAVCLPSADDDFPAGTLCATTGWG KTKYNANKTP DKLQQAALPL LSNAECKKSW GRRITDVMIC AGASGVSSCMGDSGGPLVCQ KDGAWTLVGI VSWGSDTCST SSPGVYARVTKLIPWVQKIL AAN |
| Biological Activity: | 1100 units/mg protein. One unit is defined as the amount of enzyme that will hydrolyze 1.0 ?mole of N-alpha-acetyl-L-tyrosine ethyl ester (ATEE) per min at pH 7.0 at 25�C. |
Chymotrypsinogen-B1 (CTRB1) belongs to the serine protease family ofenzymes and forms a main precursor of the pancreatic proteolytic enzymes. CTRB1is located next to a related chymotrypsinogen gene. CTRB1 is a protein codinggene which encodes different isoforms which may undergo similar processing togenerate the mature protein.
Recombinant Human CTRB1 expressed in E.coli containing 245amino acids having a Mw of 27kDa is purifiedby standard chromatography techniques.
| UniProt Protein Function: | CTRB1: is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011] |
| UniProt Protein Details: | Protein type:EC 3.4.21.1; Secreted, signal peptide; Protease; Secreted; Apoptosis Chromosomal Location of Human Ortholog: 16q23.1 Cellular Component: extracellular region; extracellular space Molecular Function:serine-type endopeptidase activity Biological Process: cobalamin metabolic process; digestion; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis; vitamin metabolic process; water-soluble vitamin metabolic process |
| NCBI Summary: | The protein encoded by this gene is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P17538 |
| NCBI GenInfo Identifier: | 117617 |
| NCBI Gene ID: | 1504 |
| NCBI Accession: | P17538.1 |
| UniProt Related Accession: | P17538 |
| Molecular Weight: | 27,870 Da |
| NCBI Full Name: | Chymotrypsinogen B |
| NCBI Synonym Full Names: | chymotrypsinogen B1 |
| NCBI Official Symbol: | CTRB1�� |
| NCBI Official Synonym Symbols: | CTRB�� |
| NCBI Protein Information: | chymotrypsinogen B |
| UniProt Protein Name: | Chymotrypsinogen B |
| Protein Family: | Chymotrypsinogen |
| UniProt Gene Name: | CTRB1�� |
| UniProt Entry Name: | CTRB1_HUMAN |
