Description
| Product Name: | Human CRISP2 Recombinant Protein |
| Product Code: | RPPB3255 |
| Size: | 10µg |
| Species: | Human |
| Target: | CRISP2 |
| Synonyms: | Cysteine-Rich Secretory Protein 2, Cancer/Testis Antigen 36, TPX1, Testis Specific Protein 1 (Probe H4-1 P3-1), Testis-Specific Protein TPX-1, CRISP-2, GAPDL5, TSP1, CT36, Glyceraldehyde-3-Phosphate Dehydrogenase-Like 5, CRISP2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Filtered colorless solution. |
| Formulation: | CRISP2 filtered (0.4�m) solution at a concentration of 0.3mg/ml in 50mM acetate buffer, pH 4, 5mM DTT and 20%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MKHHHHHHASKDPAFTALLT TQLQVQREIV NKHNELRKAV SPPASNMLKM EWSREVTTNA QRWANKCTLQ HSDPEDRKTS TRCGENLYMS SDPTSWSSAI QSWYDEILDF VYGVGPKSPN AVVGHYTQLV WYSTYQVGCG IAYCPNQDSL KYYYVCQYCP AGNNMNRKNT PYQQGTPCAG CPDDCDKGLC TNSCQYQDLL SNCDSLKNTA GCEHELLKEK CKATCLCENK IY |
Cysteine-Rich Secretory Protein 2 (CRISP2) regulates some ion channels activity and thereby regulates calcium fluxes during sperm capacitation. Amongst its related pathways are p53 signaling. Diseases related with CRISP2 include epididymitis and orchitis.
CRISP2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (22-243) containing 232 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 26.32kDa.
| UniProt Protein Function: | CRISP2: May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. Belongs to the CRISP family. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 6p12.3 Cellular Component: extracellular space Biological Process: cell-cell adhesion |
| UniProt Code: | P16562 |
| NCBI GenInfo Identifier: | 136111 |
| NCBI Gene ID: | 7180 |
| NCBI Accession: | P16562.1 |
| UniProt Secondary Accession: | P16562,Q53FF2, Q5U8Z9, Q7Z7B2, A8K8M0, |
| UniProt Related Accession: | P16562 |
| Molecular Weight: | 243 |
| NCBI Full Name: | Cysteine-rich secretory protein 2 |
| NCBI Synonym Full Names: | cysteine-rich secretory protein 2 |
| NCBI Official Symbol: | CRISP2�� |
| NCBI Official Synonym Symbols: | CT36; TPX1; TSP1; GAPDL5; CRISP-2�� |
| NCBI Protein Information: | cysteine-rich secretory protein 2; cancer/testis antigen 36; testis-specific protein TPX-1; testis specific protein 1 (probe H4-1 p3-1); glyceraldehyde-3-phosphate dehydrogenase-like 5 |
| UniProt Protein Name: | Cysteine-rich secretory protein 2 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 36; CT36; Testis-specific protein TPX-1 |
| Protein Family: | Cysteine-rich secretory protein |
| UniProt Gene Name: | CRISP2�� |
| UniProt Entry Name: | CRIS2_HUMAN |