Human CRIPT Recombinant Protein (RPPB3253)
- SKU:
- RPPB3253
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- CRIPT
- Synonyms:
- Cysteine-rich interactor of PDZ three
- cysteine-rich PDZ-binding protein
- Cysteine-rich interactor of PDZ3
- postsynaptic protein CRIPT
- Source:
- Escherichia Coli
- Uniprot:
- Q9P021
Description
| Product Name: | Human CRIPT Recombinant Protein |
| Product Code: | RPPB3253 |
| Size: | 10µg |
| Species: | Human |
| Target: | CRIPT |
| Synonyms: | Cysteine-rich interactor of PDZ three, cysteine-rich PDZ-binding protein, Cysteine-rich interactor of PDZ3, postsynaptic protein CRIPT, HSPC139. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CRIPT solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSIHHHHHH SSGLVPRGSH MGSMVCEKCE KKLGTVITPD TWKDGARNTT ESGGRKLNEN KALTSKKARF DPYGKNKFST CRICKSSVHQ PGSHYCQGCA YKKGICAMCG KKVLDTKNYK QTSV |
Cysteine-rich PDZ-binding protein, also known as CRIPT, takes part in the cytoskeletal anchoring of DLG4 in excitatory synapses.
CRIPT Human Recombinant produced in E. coli is a single polypeptide chain containing 124 amino acids (1-101) and having a molecular mass of 13.7kDa.CRIPT is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CRIPT: Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. Belongs to the CRIPT family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2p21 Cellular Component: cell soma; cytoplasm; postsynaptic density; dendrite; nucleolus; dendritic spine; dendritic shaft; nucleus; cell junction Molecular Function:protein binding; microtubule binding; protein complex binding; PDZ domain binding Biological Process: establishment of protein localization; cytoplasmic microtubule organization and biogenesis Disease: Short Stature With Microcephaly And Distinctive Facies |
| NCBI Summary: | This gene encodes a protein that binds to the PDZ3 peptide recognition domain. The encoded protein may modulates protein interactions with the cytoskeleton. A mutation in this gene resulted in short stature with microcephaly and distinctive facies. [provided by RefSeq, Jun 2014] |
| UniProt Code: | Q9P021 |
| NCBI GenInfo Identifier: | 7661798 |
| NCBI Gene ID: | 9419 |
| NCBI Accession: | NP_054890.1 |
| UniProt Related Accession: | Q9P021 |
| Molecular Weight: | 11,216 Da |
| NCBI Full Name: | cysteine-rich PDZ-binding protein |
| NCBI Synonym Full Names: | cysteine-rich PDZ-binding protein |
| NCBI Official Symbol: | CRIPT |
| NCBI Official Synonym Symbols: | SSMDF; HSPC139 |
| NCBI Protein Information: | cysteine-rich PDZ-binding protein; postsynaptic protein CRIPT; cysteine-rich interactor of PDZ3; cysteine-rich interactor of PDZ three |
| UniProt Protein Name: | Cysteine-rich PDZ-binding protein |
| UniProt Synonym Protein Names: | Cysteine-rich interactor of PDZ three; Cysteine-rich interactor of PDZ3 |
| Protein Family: | Cysteine-rich PDZ-binding protein |
| UniProt Gene Name: | CRIPT |
| UniProt Entry Name: | CRIPT_HUMAN |
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