Description
| Product Name: | Human CD58 Recombinant Protein |
| Product Code: | RPPB3082 |
| Size: | 20µg |
| Species: | Human |
| Target: | CD58 |
| Synonyms: | ag3, LFA-3, LFA3, CD58 molecule, Lymphocytefunction-associated antigen 3, Ag3, Surfaceglycoprotein LFA-3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CD58 protein solution (1mg/ml) containing 20mM Phosphatebuffer and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSFSQQIYGVVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEMESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYFKMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR |
CD58 is part of the immunoglobulin superfamily. CD58 is a ligand of the T lymphocyte CD2 protein, and is invloved in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane.
CD58 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (29-215 a.a) and having a molecular mass of 23.8kDa.CD58 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques
| UniProt Protein Function: | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
| NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
| UniProt Code: | P19256 |
| NCBI GenInfo Identifier: | 126225 |
| NCBI Gene ID: | 965 |
| NCBI Accession: | P19256.1 |
| UniProt Secondary Accession: | P19256,Q5U053, Q6IB65, Q96KI9, A8K7G5, |
| UniProt Related Accession: | P19256 |
| Molecular Weight: | 27,960 Da |
| NCBI Full Name: | Lymphocyte function-associated antigen 3 |
| NCBI Synonym Full Names: | CD58 molecule |
| NCBI Official Symbol: | CD58�� |
| NCBI Official Synonym Symbols: | ag3; LFA3; LFA-3�� |
| NCBI Protein Information: | lymphocyte function-associated antigen 3 |
| UniProt Protein Name: | Lymphocyte function-associated antigen 3 |
| UniProt Synonym Protein Names: | Surface glycoprotein LFA-3; CD_antigen: CD58 |
| Protein Family: | Lymphocyte function-associated antigen |
| UniProt Gene Name: | CD58�� |
