Human CCNI Recombinant Protein (RPPB2454)
- SKU:
- RPPB2454
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- CCNI
- Synonyms:
- Cyclin-I
- CCNI
- CYC1
- CYI
- Source:
- Escherichia Coli
- Uniprot:
- Q14094
Description
| Product Name: | Human CCNI Recombinant Protein |
| Product Code: | RPPB2454 |
| Size: | 20µg |
| Species: | Human |
| Target: | CCNI |
| Synonyms: | Cyclin-I, CCNI, CYC1, CYI. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear colorless solution. |
| Formulation: | CCNI protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMKFPGPL ENQRLSFLLE KAITREAQMW KVNVRKMPSN QNVSPSQRDE VIQWLAKLKY QFNLYPETFA LASSLLDRFL ATVKAHPKYL SCIAISCFFL AAKTVEEDER IPVLKVLARD SFCGCSSSEI LRMERIILDK LNWDLHTATP LDFLHIFHAI AVSTRPQLLF SLPKLSPSQH LAVLTKQLLH CMACNQLLQF RGSMLALAMV SLEMEKLIPD WLSLTIELLQ KAQMDSSQLI HCRELVAHHL STLQSSLPLN SVYVYRPLKH TLVTCDKGVF RLHPSSVPGP DFSKDNSKPE VPVRGTAAFY HHLPAASGCK QTSTKRKVEE MEVDDFYDGI KRLYNEDNVS ENVGSVCGTD LSRQEGHASP CPPLQPVSVM |
CCN1 is a part of the extremely conserved cyclin family, whose members are characterized by a remarkable periodicity in protein abundance through the cell cycle. Cyclins which function as regulators of CDK kinases, shows the highest similarity with cyclin G. Different cyclins display diverse expression and degradation patterns which contribute to the chronological coordination of every mitotic event. The transcript of CCN1was found to be expressed continually during cell cycle progression.
CCNI Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 400 amino acids (1-377 a.a) and having a molecular mass of 44.9kDa.CCNI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CCNI: belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 4q21.1 Biological Process: regulation of cell cycle; spermatogenesis |
| NCBI Summary: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017] |
| UniProt Code: | Q14094 |
| NCBI GenInfo Identifier: | 9296954 |
| NCBI Gene ID: | 10983 |
| NCBI Accession: | Q14094.1 |
| UniProt Related Accession: | Q14094 |
| Molecular Weight: | |
| NCBI Full Name: | Cyclin-I |
| NCBI Synonym Full Names: | cyclin I |
| NCBI Official Symbol: | CCNI |
| NCBI Official Synonym Symbols: | CYI; CYC1; CCNI1 |
| NCBI Protein Information: | cyclin-I |
| UniProt Protein Name: | Cyclin-I |
| Protein Family: | Cyclin |
| UniProt Gene Name: | CCNI |
| UniProt Entry Name: | CCNI_HUMAN |
Related Products
