Description
| Product Name: | Nanodisc Human 5HT7R Protein |
| SKU: | HDFP163 |
| Size: | 10μg |
| Target: | 5HT7R |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | 5-HT7 |
| Protein Families: | Druggable Genome, GPCR, Transmembrane. |
| Protein Description: | Human 5HT7R full length protein-synthetic nanodisc |
| Protein Pathways: | Calcium signaling pathway, Neuroactive ligand-receptor interaction. |
| Molecular Weight: | The human full length 5HT7R protein has a MW of 53.6 kDa |
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.
| Uniprot ID: | P34969 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
