HIST1H1B (Ab-172) Antibody (PACO65026)
- SKU:
- PACO65026
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Applications:
- ELISA
- IHC
- Conjugation:
- Unconjugated
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
HIST1H1B (Ab-172) Antibody (PACO65026)
The Hist1H1B Polyclonal Antibody (PAC065026) is specifically designed for research involving Hist1H1B, a protein that is involved in the regulation of gene expression and chromatin structure. The antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.Hist1H1B, also known as H1.5, is a member of the histone family involved in packaging DNA into chromatin. It plays a crucial role in maintaining chromatin structure and gene expression regulation. The Hist1H1B antibody binds specifically to Hist1H1B protein, allowing for the detection and analysis of its expression levels in different cell types.
Research on Hist1H1B is important for understanding its role in various biological processes, including development, differentiation, and disease. Aberrant expression of Hist1H1B has been implicated in cancer and other diseases, making it a potential target for therapeutic interventions. Studying Hist1H1B can provide valuable insights into the molecular mechanisms underlying these conditions and help in the development of novel treatments.
Product Name: | HIST1H1B (Ab-172) Antibody |
Product Code: | PACO65026 |
Size: | 50µL |
Target Names: | HIST1H1B |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, IHC; Recommended dilution: IHC:1:10-1:100 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Synthesized peptide derived from Human Histone H1.5 protein (164-176aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5 |
Uniprot ID: | P16401 |
Background: | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). |
Research Area: | Epigenetics and Nuclear Signaling |