The Transportin-3 (TNPO3) Polyclonal Antibody (CAB19774) is specifically designed for research involving the TNPO3 protein, a key player in nucleocytoplasmic transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to TNPO3, this antibody enables precise detection and analysis of the protein in various cell types, making it an ideal tool for studies in molecular biology and cellular transport mechanisms.TNPO3 plays a crucial role in mediating the transportation of proteins and RNA between the nucleus and cytoplasm, influencing various cellular processes such as gene expression and signaling pathways.
Its intricate involvement in nucleocytoplasmic transport makes it a promising target for research in fields like virology, cancer biology, and neurodegenerative diseases. Understanding the functions of TNPO3 can provide valuable insights into the mechanisms underlying these diseases and facilitate the development of targeted therapies.
Product Name:
Transportin 3 (TNPO3) Rabbit Monoclonal Antibody
SKU:
CAB19774
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 824-923 of human Transportin 3 (Transportin 3 (TNPO3)) (Q9Y5L0).
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Several protein-coding and non-coding transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23534
Clone Number:
ARC2310
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Transportin 3 (Transportin 3 (TNPO3)) Rabbit mAb (CAB19774) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
