The SMARCD3 Polyclonal Antibody (CAB20174) is a powerful tool for researchers studying SMARCD3, a key component of the SWI/SNF chromatin remodeling complex. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for use in Western blotting, immunofluorescence, and immunohistochemistry applications.SMARCD3 is known to play a crucial role in gene regulation and chromatin remodeling processes, impacting various cellular functions such as cell proliferation, differentiation, and DNA repair. Dysregulation of SMARCD3 has been linked to cancer development and progression, making it a promising target for cancer research and therapeutic interventions.
By targeting the SMARCD3 protein, researchers can gain insights into its function and molecular pathways, paving the way for the development of novel cancer therapies and diagnostic tools. The SMARCD3 Polyclonal Antibody is an essential tool for investigating the role of SMARCD3 in different biological processes and disease states, advancing our understanding of chromatin remodeling and its implications in human health.
Product Name:
SMARCD3 Rabbit Polyclonal Antibody
SKU:
CAB20174
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 275-440 of human SMARCD3 (NP_001003801.1).
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
6604
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMARCD3 Rabbit pAb (CAB20174) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
