The SCAF4 Polyclonal Antibody (CAB20724) is a valuable tool for researchers studying SCAF4, a protein involved in RNA splicing and transcription regulation. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in immunofluorescence and immunohistochemistry applications. By binding to the SCAF4 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in molecular biology and gene expression regulation.SCAF4 plays a crucial role in coordinating the splicing of precursor mRNA and influencing gene expression, making it a key player in cellular processes.
Its involvement in RNA metabolism and transcriptional activation implicates SCAF4 in diverse biological functions, including cell proliferation and differentiation. Research into SCAF4's mechanisms is vital for understanding its impact on gene regulation and identifying potential therapeutic targets for diseases related to altered RNA processing and transcriptional dysregulation.
Product Name:
SCAF4 Polyclonal Antibody
SKU:
CAB20724
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-248 of human SCAF4 (NP_065757.1).
This gene likely encodes a member of the arginine/serine-rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
57466
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human esophagus using SCAF4 Rabbit pAb (CAB20724) at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
