The RRP8 Polyclonal Antibody (CAB20557) is a valuable tool for researchers studying the RRP8 protein, which plays a crucial role in RNA processing and ribosome biogenesis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RRP8 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in molecular biology and genetics.RRP8 is a key component of the exosome complex, involved in RNA degradation and processing, as well as ribosomal RNA maturation.
Understanding the function of RRP8 is essential for unraveling the complexities of gene expression regulation and RNA metabolism. Research on RRP8 can provide valuable insights into diseases such as cancer, neurodegenerative disorders, and developmental abnormalities, making this antibody a valuable tool for advancing knowledge in these fields.
Product Name:
RRP8 Rabbit Polyclonal Antibody
SKU:
CAB20557
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RRP8 (NP_056139.1).
Enables methylated histone binding activity. Involved in several processes, including cellular response to glucose starvation; intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of gene expression. Located in several cellular components, including cytosol; nuclear lumen; and rDNA heterochromatin. Part of chromatin silencing complex.
Purification Method:
Affinity purification
Gene ID:
23378
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RRP8 antibody (CAB20557) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
