The anti-ROR Beta Antibody (CAB19753) is a valuable tool for researchers studying the Retinoic Acid Receptor Related Orphan Receptor Beta (ROR Beta) protein. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the ROR Beta protein, researchers can effectively detect and analyze this key transcription factor in a variety of cell types.ROR Beta is a crucial regulator of gene expression involved in various biological processes, including development, metabolism, and immune function. Dysregulation of ROR Beta has been implicated in conditions such as autoimmune diseases, cancer, and metabolic disorders, making it an attractive target for therapeutic interventions.
Research using the anti-ROR Beta Antibody can provide insights into the mechanisms underlying these diseases and aid in the development of targeted treatments.Overall, the anti-ROR Beta Antibody (CAB19753) is a reliable tool for researchers investigating the functions and implications of the ROR Beta protein in a diverse range of biological contexts. Its specificity, sensitivity, and validation for Western blot applications make it an essential asset for studies in immunology, oncology, and metabolic disorders.
Product Name:
RORβ Rabbit Monoclonal Antibody
SKU:
CAB19753
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RORβ (Q92753).
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm.
Purification Method:
Affinity purification
Gene ID:
6096
Clone Number:
ARC2279
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RORβ Rabbit mAb (CAB19753) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
