The Anti-Renalase Antibody (CAB19797) is a valuable tool for researchers investigating the role of renalase, an enzyme implicated in various physiological processes including blood pressure regulation, metabolism, and cardiovascular function. This polyclonal antibody, generated in rabbits, is highly specific to renalase and is validated for use in a variety of applications, including immunohistochemistry and flow cytometry.Renalase, a secreted enzyme primarily expressed in the kidneys, has been shown to play a critical role in the modulation of blood pressure and the regulation of oxidative stress.
Dysregulation of renalase has been associated with several diseases, including hypertension, chronic kidney disease, and heart failure, making it a promising target for therapeutic interventions.By utilizing the Anti-Renalase Antibody, researchers can accurately detect and quantify renalase levels in tissue samples or cell cultures, providing valuable insights into the enzyme's function in health and disease. This antibody is an essential tool for studies in renal physiology, cardiovascular research, and the development of novel therapeutic strategies targeting renalase activity.
Product Name:
Renalase Rabbit Monoclonal Antibody
SKU:
CAB19797
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Renalase (Q5VYX0).
Enables several functions, including NADH binding activity; epinephrine binding activity; and monoamine oxidase activity. Involved in negative regulation of blood pressure and negative regulation of heart rate. Located in extracellular region. Implicated in essential hypertension and hypertension. Biomarker of end stage renal disease.
Purification Method:
Affinity purification
Gene ID:
55328
Clone Number:
ARC2324
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Renalase Rabbit mAb (CAB19797) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
