The Anti-PAX9 Antibody (CAB19741) is a highly specific and sensitive tool for researchers studying the PAX9 protein, a transcription factor involved in the development of tissues such as teeth and bones. This polyclonal antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.PAX9 is essential for the formation and differentiation of different cell types during embryonic development, making it a key player in various developmental processes. Research has shown that mutations in the PAX9 gene are linked to dental anomalies and craniofacial abnormalities, highlighting the importance of studying its function in both normal and pathological conditions.
By targeting the PAX9 protein, researchers can gain valuable insights into its role in developmental biology, as well as its potential implications in diseases such as cleft palate, tooth agenesis, and other developmental disorders. The Anti-PAX9 Antibody (CAB19741) provides a reliable tool for investigating the function and expression of PAX9 in different biological contexts, making it a valuable asset for studies in genetics, molecular biology, and regenerative medicine.
Product Name:
PAX9 Rabbit Monoclonal Antibody
SKU:
CAB19741
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAX9 (P55771).
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3.
Purification Method:
Affinity purification
Gene ID:
5083
Clone Number:
ARC2267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PAX9 Rabbit mAb (CAB19741) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
