The NUP107 Polyclonal Antibody (CAB20955) is a valuable tool for researchers studying the nuclear pore complex protein NUP107. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the NUP107 protein, this antibody enables researchers to detect and analyze NUP107 in various cell types, making it ideal for investigations in cell biology, nuclear transport, and gene regulation.
NUP107 is a key component of the nuclear pore complex, a large protein complex that regulates the transport of molecules in and out of the cell nucleus. Dysregulation of NUP107 has been implicated in various diseases, including cancer, neurodegenerative disorders, and viral infections. By studying NUP107 using this antibody, researchers can gain insights into its role in these diseases and potentially identify novel therapeutic targets for intervention.
Product Name:
Nup107 Monoclonal Antibody
SKU:
CAB20955
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Nup107 (P57740).
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Purification Method:
Affinity purification
Gene ID:
57122
Clone Number:
ARC2942
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Nup107 antibody (CAB20955) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
