The NPAS3 Polyclonal Antibody (CAB20561) is a valuable tool for researchers studying NPAS3, a transcription factor that plays a crucial role in neuronal development and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blotting experiments.NPAS3 is known for its involvement in regulating the expression of genes related to neurodevelopment and synaptic plasticity. Dysregulation of NPAS3 has been linked to various neurological disorders, including schizophrenia and bipolar disorder.
By targeting NPAS3 with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.With its ability to specifically detect NPAS3 in various cell types, the NPAS3 Polyclonal Antibody is an essential tool for advancing research in neuroscience and psychiatric disorders. By studying the function and regulation of NPAS3, scientists can uncover new avenues for developing treatments that target the underlying causes of these debilitating conditions.
Product Name:
NPAS3 Rabbit Polyclonal Antibody
SKU:
CAB20561
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human NPAS3 (NP_001158221.1).
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NPAS3 antibody (CAB20561) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
