The MAN2A2 Monoclonal Antibody (CAB19323) is a vital tool for researchers studying the MAN2A2 protein, a key enzyme involved in N-linked glycan processing. This antibody, developed for use in various research applications, is specifically designed to detect and analyze MAN2A2 in human samples. Raised in rabbits, it offers high reactivity and specificity in Western blot experiments.MAN2A2, a critical enzyme in glycosylation pathways, plays a pivotal role in the biosynthesis and processing of complex oligosaccharides. Dysregulation of MAN2A2 has been linked to various diseases, including cancer and congenital disorders.
By targeting MAN2A2, researchers can gain valuable insights into glycan processing and its implications in disease pathology.Overall, the MAN2A2 Monoclonal Antibody (CAB19323) provides a reliable tool for investigating the role of MAN2A2 in cellular processes and disease development. Its applications in glycobiology, cancer research, and drug development make it an essential component in advancing our understanding of glycan-related diseases.
Product Name:
MAN2A2 Polyclonal Antibody
SKU:
CAB19323
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MAN2A2 (NP_006113.2).
Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing and protein deglycosylation. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane.
Purification Method:
Affinity purification
Gene ID:
4122
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using MAN2A2 Rabbit pAb (CAB19323) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
