The LLGL1 Polyclonal Antibody (CAB20205) offered by AssayGenie is a valuable tool for researchers studying the LLGL1 protein, which plays a crucial role in cell polarity and cell division processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.LLGL1, or lethal giant larvae homolog 1, is a key regulator of cell polarity and asymmetric cell division, important for maintaining tissue organization and preventing tumor formation. By targeting the LLGL1 protein, researchers can gain insights into its function in various cell types and its implications in cancer biology.
Understanding the role of LLGL1 in cell polarity and division is essential for unraveling its contributions to disease states such as cancer and developmental disorders. With the LLGL1 Polyclonal Antibody, researchers can investigate the mechanisms underlying LLGL1 function and potentially identify novel therapeutic targets for cancer treatment and other diseases related to cell polarity dysregulation.
Product Name:
LLGL1 Rabbit Polyclonal Antibody
SKU:
CAB20205
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human LLGL1 (NP_004131.3).
This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
3996
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LLGL1 Rabbit pAb (CAB20205) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
