The Anti-IL1RN Antibody (CAB21089) is a high-quality polyclonal antibody designed for research involving IL1RN, a crucial regulator of immune responses. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in a variety of applications, including Western blotting. IL1RN, also known as interleukin 1 receptor antagonist, plays a vital role in regulating the inflammatory response by binding to interleukin-1 receptors and inhibiting their activity. Dysregulation of IL1RN has been linked to various inflammatory diseases, making it a promising target for research in immunology and drug development.
By enabling the detection and analysis of IL1RN protein in different cell types, this antibody facilitates a deeper understanding of the mechanisms underlying immune regulation and inflammation. This product is essential for studies investigating diseases like arthritis, inflammatory bowel disease, and other conditions where IL1RN dysregulation plays a role. Unlock the potential of IL1RN research with the Anti-IL1RN Antibody (CAB21089).
Product Name:
IL1RN Polyclonal Antibody
SKU:
CAB21089
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-178 of mouse IL1RN (NP_001034790.1).
cytoplasm, extracellular region, extracellular space
Calculated MW:
20kDa
Observed MW:
18kDa
Predicted to enable cytokine receptor binding activity. Acts upstream of or within insulin secretion and lipid metabolic process. Located in extracellular region and vesicle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist).
Purification Method:
Affinity purification
Gene ID:
16181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL1RN antibody (CAB21089) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
