Phospho-GATA1 (S142) Antibody (PACO03825)
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주문- SKU:
- PACO03825
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-GATA1 (S142) Antibody |
Antibody SKU: | PACO03825 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IP |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IP:2-5ug |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from human GATA-1 around the phosphorylation site of S142. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | GATA1; ERYF1; GF1; Erythroid transcription factor; Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein |
UniProt Protein Function: | Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781). |
NCBI Summary: | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008] |
UniProt Code: | P15976 |
NCBI GenInfo Identifier: | 120956 |
NCBI Gene ID: | 2623 |
NCBI Accession: | P15976.1 |
UniProt Secondary Accession: | P15976,Q96GB8, |
UniProt Related Accession: | P15976 |
Molecular Weight: | 34,232 Da |
NCBI Full Name: | Erythroid transcription factor |
NCBI Synonym Full Names: | GATA binding protein 1 |
NCBI Official Symbol: | GATA1 |
NCBI Official Synonym Symbols: | GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1 |
NCBI Protein Information: | erythroid transcription factor |
UniProt Protein Name: | Erythroid transcription factor |
UniProt Synonym Protein Names: | Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein |
Protein Family: | GATA transcription factor |
UniProt Gene Name: | GATA1 |