GATA1 Antibody (PACO45854)
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주문- SKU:
- PACO45854
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GATA1 Antibody (PACO45854) |
Antibody SKU: | PACO45854 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Erythroid transcription factor protein (39-153AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: GATA1 antibody at 7µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 43, 36, 35 kDa. Observed band size: 43 kDa.. | |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO45854 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human melanoma using PACO45854 at dilution of 1:100. |
Background: | Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS. |
Synonyms: | Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein), GATA1, ERYF1 GF1 |
UniProt Protein Function: | Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781). |
NCBI Summary: | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008] |
UniProt Code: | P15976 |
NCBI GenInfo Identifier: | 120956 |
NCBI Gene ID: | 2623 |
NCBI Accession: | P15976.1 |
UniProt Secondary Accession: | P15976,Q96GB8, |
UniProt Related Accession: | P15976 |
Molecular Weight: | 34,232 Da |
NCBI Full Name: | Erythroid transcription factor |
NCBI Synonym Full Names: | GATA binding protein 1 |
NCBI Official Symbol: | GATA1 |
NCBI Official Synonym Symbols: | GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1 |
NCBI Protein Information: | erythroid transcription factor |
UniProt Protein Name: | Erythroid transcription factor |
UniProt Synonym Protein Names: | Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein |
Protein Family: | GATA transcription factor |
UniProt Gene Name: | GATA1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |