Human FBPase 1/FBP1 Recombinant Protein (RPES3740)

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SKU:
RPES3740
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human FBPase 1/FBP1 Recombinant Protein

Fructose-1;6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein; which catalyzes the hydrolysis of fructose 1;6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state; or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

Product Name:Human FBPase 1/FBP1 Recombinant Protein (RPES3740)
Product Code:RPES3740
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Fructose-1,6-Bisphosphatase 1, FBPase 1, D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP
Accession:P09467
Sequence:Ala2-Gln338
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Fructose-1;6-Bisphosphatase 1 is produced by our E.coli expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus.
Purity:> 85 % as determined by reducing SDS-PAGE.
Mol Mass:37.9 kDa
AP Mol Mass:38 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 200mM NaCl; 1mM DTT; 1mM EDTA; 20% Glycerol; pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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