YWHAH Antibody (PACO23302)
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주문- SKU:
- PACO23302
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | YWHAH Antibody (PACO23302) |
Antibody SKU: | PACO23302 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human 14-3-3 eta . |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, using 14-3-3 eta antibody. | |
Immunofluorescence analysis of HeLa cells, using 14-3-3 eta antibody. |
Background: | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. |
Synonyms: | 14-3-3 protein eta; Protein AS1; YWHAH; YWHA1; |
UniProt Protein Function: | 14-3-3 eta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Adaptor/scaffold Chromosomal Location of Human Ortholog: 22q12.3 Cellular Component: cytoplasmic vesicle membrane; cytoplasm; plasma membrane; cytosol Molecular Function:insulin-like growth factor receptor binding; protein domain specific binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding Biological Process: intracellular protein transport; substantia nigra development; regulation of neuron differentiation; apoptosis; glucocorticoid receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of synaptic plasticity; glucocorticoid catabolic process; negative regulation of dendrite morphogenesis; regulation of sodium ion transport |
NCBI Summary: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009] |
UniProt Code: | Q04917 |
NCBI GenInfo Identifier: | 4507951 |
NCBI Gene ID: | 7533 |
NCBI Accession: | NP_003396.1 |
UniProt Related Accession: | Q04917 |
Molecular Weight: | 28,219 Da |
NCBI Full Name: | 14-3-3 protein eta |
NCBI Synonym Full Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
NCBI Official Symbol: | YWHAH |
NCBI Official Synonym Symbols: | YWHA1 |
NCBI Protein Information: | 14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide |
UniProt Protein Name: | 14-3-3 protein eta |
UniProt Synonym Protein Names: | Protein AS1 |
Protein Family: | 14-3-3 protein |
UniProt Gene Name: | YWHAH |
UniProt Entry Name: | 1433F_HUMAN |
Antibodies | ELISA Kits |
Anti-YWHAH Antibody (CAB9079) | Human 14-3-3 protein eta (YWHAH) ELISA Kit (HUFI04789) |
YWHAH Antibody (PACO05316) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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