XRCC2 Antibody (PACO01709)
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주문- SKU:
- PACO01709
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | XRCC2 Antibody |
Antibody SKU: | PACO01709 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the C-terminal region of human XRCC2. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | XRCC2; DNA repair protein XRCC2; X-ray repair cross-complementing protein 2 |
UniProt Protein Function: | XRCC2: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Belongs to the RecA family. RAD51 subfamily. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 7q36.1 Cellular Component: centrosome; nucleoplasm; replication fork Molecular Function:DNA-dependent ATPase activity; double-stranded DNA binding; endodeoxyribonuclease activity; four-way junction DNA binding; protein binding; recombinase activity; single-stranded DNA binding Biological Process: centrosome organization and biogenesis; DNA repair; DNA synthesis during DNA repair; double-strand break repair via homologous recombination; meiosis; meiotic DNA recombinase assembly; meiotic recombination; mitotic cell cycle; mitotic recombination; response to ionizing radiation; strand displacement; strand invasion |
NCBI Summary: | This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008] |
UniProt Code: | O43543 |
NCBI GenInfo Identifier: | 20140429 |
NCBI Gene ID: | 7516 |
NCBI Accession: | O43543.1 |
UniProt Secondary Accession: | O43543,B2R925, |
UniProt Related Accession: | O43543 |
Molecular Weight: | 31,956 Da |
NCBI Full Name: | DNA repair protein XRCC2 |
NCBI Synonym Full Names: | X-ray repair cross complementing 2 |
NCBI Official Symbol: | XRCC2 |
NCBI Official Synonym Symbols: | FANCU |
NCBI Protein Information: | DNA repair protein XRCC2 |
UniProt Protein Name: | DNA repair protein XRCC2 |
UniProt Synonym Protein Names: | X-ray repair cross-complementing protein 2 |
Protein Family: | DNA repair protein |
UniProt Gene Name: | XRCC2 |
UniProt Entry Name: | XRCC2_HUMAN |