SWAP70 Antibody (PACO42046)
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주문- SKU:
- PACO42046
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SWAP70 Antibody (PACO42046) |
Antibody SKU: | PACO42046 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Switch-associated protein 70 protein (1-300AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: SWAP70 antibody at 10µg/ml. Lane 1: NIH/3T3 whole cell lysate. Lane 2: HepG2 whole cell lysate. Lane 3: Raji whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 69 kDa. Observed band size: 69 kDa. |
Background: | Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). |
Synonyms: | Switch-associated protein 70 (SWAP-70), SWAP70, KIAA0640 |
UniProt Protein Function: | SWAP-70: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion. |
UniProt Protein Details: | Protein type:GEF; GEF, Rac/Rho Chromosomal Location of Human Ortholog: 11p15.4 Cellular Component: cell-cell adherens junction; cytoplasm Molecular Function:protein binding |
UniProt Code: | Q9UH65 |
NCBI GenInfo Identifier: | 74753323 |
NCBI Gene ID: | 23075 |
NCBI Accession: | Q9UH65.1 |
UniProt Secondary Accession: | Q9UH65,O75135, Q7LCY6, Q9P061, Q9P0Z8, D3DQV1, |
UniProt Related Accession: | Q9UH65 |
Molecular Weight: | 68,998 Da |
NCBI Full Name: | Switch-associated protein 70 |
NCBI Synonym Full Names: | SWAP switching B-cell complex subunit 70 |
NCBI Official Symbol: | SWAP70 |
NCBI Official Synonym Symbols: | HSPC321; SWAP-70 |
NCBI Protein Information: | switch-associated protein 70 |
UniProt Protein Name: | Switch-associated protein 70 |
Protein Family: | Switch-associated protein |
UniProt Gene Name: | SWAP70 |
Antibodies | ELISA Kits |
Anti-SWAP70 Antibody (CAB14857) | Human SWAP70 ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |