SWAP70 Antibody (PACO17381)
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주문- SKU:
- PACO17381
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SWAP70 Antibody (PACO17381) |
Antibody SKU: | PACO17381 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human SWAP70 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO17381(SWAP70 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17381(SWAP70 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). |
Synonyms: | SWAP switching B-cell complex 70kDa subunit |
UniProt Protein Function: | SWAP-70: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion. |
UniProt Protein Details: | Protein type:GEF; GEF, Rac/Rho Chromosomal Location of Human Ortholog: 11p15.4 Cellular Component: cell-cell adherens junction; cytoplasm Molecular Function:protein binding |
UniProt Code: | Q9UH65 |
NCBI GenInfo Identifier: | 74753323 |
NCBI Gene ID: | 23075 |
NCBI Accession: | Q9UH65.1 |
UniProt Secondary Accession: | Q9UH65,O75135, Q7LCY6, Q9P061, Q9P0Z8, D3DQV1, |
UniProt Related Accession: | Q9UH65 |
Molecular Weight: | 68,998 Da |
NCBI Full Name: | Switch-associated protein 70 |
NCBI Synonym Full Names: | SWAP switching B-cell complex subunit 70 |
NCBI Official Symbol: | SWAP70 |
NCBI Official Synonym Symbols: | HSPC321; SWAP-70 |
NCBI Protein Information: | switch-associated protein 70 |
UniProt Protein Name: | Switch-associated protein 70 |
Protein Family: | Switch-associated protein |
UniProt Gene Name: | SWAP70 |
Antibodies | ELISA Kits |
Anti-SWAP70 Antibody (CAB14857) | Human SWAP70 ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |