RNASE3 Antibody (PACO00736)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO00736
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RNASE3 Antibody |
Antibody SKU: | PACO00736 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the C-terminal region of human ECP. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3 |
UniProt Protein Function: | RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; EC 3.1.27.-; Ribonuclease Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: extracellular space; extracellular region Molecular Function:nucleic acid binding; endonuclease activity; ribonuclease activity Biological Process: defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process; antibacterial humoral response |
NCBI Summary: | The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014] |
UniProt Code: | P12724 |
NCBI GenInfo Identifier: | 147744558 |
NCBI Gene ID: | 6037 |
NCBI Accession: | P12724.2 |
UniProt Secondary Accession: | P12724,Q4VBC1, Q8WTP7, Q8WZ62, Q9GZN9, |
UniProt Related Accession: | P12724 |
Molecular Weight: | 18kDa |
NCBI Full Name: | Eosinophil cationic protein |
NCBI Synonym Full Names: | ribonuclease, RNase A family, 3 |
NCBI Official Symbol: | RNASE3 |
NCBI Official Synonym Symbols: | ECP; RNS3 |
NCBI Protein Information: | eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease |
UniProt Protein Name: | Eosinophil cationic protein |
UniProt Synonym Protein Names: | Ribonuclease 3; RNase 3 |
Protein Family: | Eosinophil cationic protein |
UniProt Gene Name: | RNASE3 |
UniProt Entry Name: | ECP_HUMAN |