PRKG2 (Ab-126) Antibody (PACO21609)
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주문- SKU:
- PACO21609
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PRKG2 (Ab-126) Antibody (PACO21609) |
Antibody SKU: | PACO21609 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized non-phosphopeptide derived from human PKG2 around the phosphorylation site of serine 126 (G-V-S(p)-A-E). |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from 293 cells, treated with anisomycin (25ug/ml, 30mins), using PKG2 (Ab-126) antibody. |
Background: | This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. Fujii M., FEBS Lett. 375:263-267(1995). |
Synonyms: | CGK 2; cGKII; cGMP-dependent protein kinase 2; EC 2.7.11.12; KGP2 |
UniProt Protein Function: | PKG2: an AGC kinase of the PKG family. Type II cGMP-dependent protein kinase is expressed at high levels in brain, lung and intestinal mucosa. |
UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, AGC; EC 2.7.11.12; Protein kinase, Ser/Thr (non-receptor); AGC group; PKG family Chromosomal Location of Human Ortholog: 4q13.1-q21.1 Cellular Component: apical plasma membrane; cytosol; nuclear membrane Molecular Function:ATP binding; cGMP binding; cGMP-dependent protein kinase activity; protein homodimerization activity; protein kinase activity Biological Process: blood coagulation; circadian regulation of gene expression; nitric oxide metabolic process; protein amino acid phosphorylation; regulation of nitric-oxide synthase activity; signal transduction |
NCBI Summary: | This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q13237 |
NCBI GenInfo Identifier: | 6226833 |
NCBI Gene ID: | 5593 |
NCBI Accession: | Q13237.1 |
UniProt Secondary Accession: | Q13237,O00125, O60916, B4DMX3, E7EPE6, |
UniProt Related Accession: | Q13237 |
Molecular Weight: | 84,398 Da |
NCBI Full Name: | cGMP-dependent protein kinase 2 |
NCBI Synonym Full Names: | protein kinase, cGMP-dependent, type II |
NCBI Official Symbol: | PRKG2 |
NCBI Official Synonym Symbols: | cGK2; cGKII; PRKGR2 |
NCBI Protein Information: | cGMP-dependent protein kinase 2 |
UniProt Protein Name: | cGMP-dependent protein kinase 2 |
UniProt Synonym Protein Names: | cGMP-dependent protein kinase II; cGKII |
Protein Family: | cGMP-dependent protein kinase |
UniProt Gene Name: | PRKG2 |
UniProt Entry Name: | KGP2_HUMAN |
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