PIK3R4 Antibody (PACO50958)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO50958
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | PIK3R4 Antibody (PACO50958) |
Antibody SKU: | PACO50958 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phosphoinositide 3-kinase regulatory subunit 4 protein (1300-1358AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO50958 at dilution of 1:100. | |
Immunofluorescent analysis of Hela cells using PACO50958 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO50958 at dilution of 1:100. |
Background: | Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2. |
Synonyms: | Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein), PIK3R4, VPS15 |
UniProt Protein Function: | PIK3R4: Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. |
UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Kinase, lipid; EC 2.7.11.1; Other group; VPS15 family Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: membrane; late endosome; nuclear pore; axoneme; cytosol Molecular Function:protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity Biological Process: macroautophagy; phospholipid metabolic process; late endosome to vacuole transport; toll-like receptor signaling pathway; phosphatidylinositol biosynthetic process; insulin receptor signaling pathway; innate immune response; protein targeting to vacuole; toll-like receptor 9 signaling pathway; peroxisome degradation; protein amino acid phosphorylation |
UniProt Code: | Q99570 |
NCBI GenInfo Identifier: | 74762700 |
NCBI Gene ID: | 30849 |
NCBI Accession: | Q99570.3 |
UniProt Secondary Accession: | Q99570,Q2TBF4, |
UniProt Related Accession: | Q99570 |
Molecular Weight: | 1358 |
NCBI Full Name: | Phosphoinositide 3-kinase regulatory subunit 4 |
NCBI Synonym Full Names: | phosphoinositide-3-kinase, regulatory subunit 4 |
NCBI Official Symbol: | PIK3R4 |
NCBI Official Synonym Symbols: | p150; VPS15 |
NCBI Protein Information: | phosphoinositide 3-kinase regulatory subunit 4; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; phosphoinositide 3-kinase adaptor protein; phosphatidylinositol 3-kinase-associated p150; phosphoinositide-3-kinase, regulatory subunit 4, p150 |
UniProt Protein Name: | Phosphoinositide 3-kinase regulatory subunit 4 |
UniProt Synonym Protein Names: | PI3-kinase p150 subunit; Phosphoinositide 3-kinase adaptor protein |
Protein Family: | Phosphoinositide 3-kinase regulatory |
UniProt Gene Name: | PIK3R4 |
UniProt Entry Name: | PI3R4_HUMAN |