PIK3R4 Antibody (PACO19200)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO19200
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | PIK3R4 Antibody (PACO19200) |
Antibody SKU: | PACO19200 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human PIK3R4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19200(PIK3R4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19200(PIK3R4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Phosphoinositide 3-kinase regulatory subunit 4, also known as PI3-kinase regulatory subunit 4 or PI3-kinase p150 subunit or phosphoinositide 3-kinase adaptor protein, or VPS15 is an enzyme that in humans is encoded by the PIK3R4 gene. The PI3-kinases regulate cellular signaling networks that are involved in processes linked to the survival, growth, proliferation, metabolism and specialized differentiated functions of cells. The subversion of this network is common in cancer and has also been linked to disorders of inflammation. |
Synonyms: | phosphoinositide-3-kinase, regulatory subunit 4 |
UniProt Protein Function: | PIK3R4: Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. |
UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Kinase, lipid; EC 2.7.11.1; Other group; VPS15 family Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: membrane; late endosome; nuclear pore; axoneme; cytosol Molecular Function:protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity Biological Process: macroautophagy; phospholipid metabolic process; late endosome to vacuole transport; toll-like receptor signaling pathway; phosphatidylinositol biosynthetic process; insulin receptor signaling pathway; innate immune response; protein targeting to vacuole; toll-like receptor 9 signaling pathway; peroxisome degradation; protein amino acid phosphorylation |
UniProt Code: | Q99570 |
NCBI GenInfo Identifier: | 74762700 |
NCBI Gene ID: | 30849 |
NCBI Accession: | Q99570.3 |
UniProt Secondary Accession: | Q99570,Q2TBF4, |
UniProt Related Accession: | Q99570 |
Molecular Weight: | 1358 |
NCBI Full Name: | Phosphoinositide 3-kinase regulatory subunit 4 |
NCBI Synonym Full Names: | phosphoinositide-3-kinase, regulatory subunit 4 |
NCBI Official Symbol: | PIK3R4 |
NCBI Official Synonym Symbols: | p150; VPS15 |
NCBI Protein Information: | phosphoinositide 3-kinase regulatory subunit 4; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; phosphoinositide 3-kinase adaptor protein; phosphatidylinositol 3-kinase-associated p150; phosphoinositide-3-kinase, regulatory subunit 4, p150 |
UniProt Protein Name: | Phosphoinositide 3-kinase regulatory subunit 4 |
UniProt Synonym Protein Names: | PI3-kinase p150 subunit; Phosphoinositide 3-kinase adaptor protein |
Protein Family: | Phosphoinositide 3-kinase regulatory |
UniProt Gene Name: | PIK3R4 |
UniProt Entry Name: | PI3R4_HUMAN |