NT5E Antibody (PACO15743)
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주문- SKU:
- PACO15743
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | NT5E Antibody (PACO15743) |
Antibody SKU: | PACO15743 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human NT5E |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15743(NT5E Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15743(NT5E Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | 5'-nucleotidase, ecto (CD73) |
UniProt Protein Function: | NT5E: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Homodimer; disulfide-linked. Belongs to the 5'-nucleotidase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.1.3.5; Membrane protein, integral; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Phosphatase (non-protein); Membrane protein, GPI anchor; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide Chromosomal Location of Human Ortholog: 6q14-q21 Cellular Component: cell surface; membrane; cytoplasm; plasma membrane Molecular Function:5'-nucleotidase activity; metal ion binding; nucleotide binding Biological Process: pyrimidine nucleoside catabolic process; dephosphorylation; pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; adenosine biosynthetic process; negative regulation of inflammatory response; purine nucleotide catabolic process; DNA metabolic process; purine base metabolic process; AMP catabolic process Disease: Calcification Of Joints And Arteries |
NCBI Summary: | The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] |
UniProt Code: | P21589 |
NCBI GenInfo Identifier: | 112825 |
NCBI Gene ID: | 4907 |
NCBI Accession: | P21589.1 |
UniProt Related Accession: | P21589 |
Molecular Weight: | |
NCBI Full Name: | 5'-nucleotidase |
NCBI Synonym Full Names: | 5'-nucleotidase ecto |
NCBI Official Symbol: | NT5E |
NCBI Official Synonym Symbols: | NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA |
NCBI Protein Information: | 5'-nucleotidase |
UniProt Protein Name: | 5'-nucleotidase |
UniProt Synonym Protein Names: | Ecto-5'-nucleotidase; CD_antigen: CD73 |
UniProt Gene Name: | NT5E |
UniProt Entry Name: | 5NTD_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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