Human UBE2C Recombinant Protein (RPES1981)
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주문- SKU:
- RPES1981
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
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Description
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Human UBE2C Recombinant Protein
Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).
Product Name: | Human UBE2C Recombinant Protein (RPES1981) |
Product Code: | RPES1981 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C, UBCH10 |
Accession: | O00762 |
Sequence: | Met 1-Pro179 |
Fusion tag: | N-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Ubiquitin-Conjugating Enzyme E2 C is produced by our E.coli expression system and the target gene encoding Met1-Pro179 is expressed with a 6His tag at the N-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 23.3 kDa |
AP Mol Mass: | 18-19 kDa |
Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB,150mM NaCl, pH 7.0. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |