Human TNFRSF1B/CD120b Recombinant Protein (RPES4098)

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SKU:
RPES4098
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human TNFRSF1B/CD120b Recombinant Protein

Tumor necrosis factor receptor superfamily member 1B is a 461 amino acids protein that belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction; and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis; which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Product Name:Human TNFRSF1B/CD120b Recombinant Protein (RPES4098)
Product Code:RPES4098
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, TBP-2, TBPII, TNFRSF1B, TNFBR, TNFR2, Tumor Necrosis Factor Receptor II
Accession:P20333
Sequence:Leu23-Asp257
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human TNFRSF1B is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:26.2 kDa
AP Mol Mass:40 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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