Human THOP1 Recombinant Protein (RPES0647)

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SKU:
RPES0647
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human THOP1 Recombinant Protein

Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

Product Name:Human THOP1 Recombinant Protein (RPES0647)
Product Code:RPES0647
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1
Accession:P52888
Sequence:Lys2-Cys689
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:80.0 kDa
AP Mol Mass:85 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB, 100mM NaCl, 10% Glycerol, pH 7.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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