Human PPCDC Recombinant Protein (RPES1960)

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SKU:
RPES1960
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human PPCDC Recombinant Protein

Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and MrsD, all of which use a tightly bound Flavin cofactor to oxidize the Thiol moiety of the substrate to a Thioaldehyde.

Product Name:Human PPCDC Recombinant Protein (RPES1960)
Product Code:RPES1960
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Phosphopantothenoylcysteine Decarboxylase, PPC-DC, PPCDC, COAC
Accession:Q96CD2
Sequence:Met 1-Ser204
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Phosphopantothenoylcysteine Decarboxylase is produced by our E.coli expression system and the target gene encoding Met1-Ser204 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:24.6 kDa
AP Mol Mass:27 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 50mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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