Human MOG Recombinant Protein (RPES4946)

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SKU:
RPES4946
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human MOG Recombinant Protein

Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space which allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like disease in experimental animals;namely experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.

Product Name:Human MOG Recombinant Protein (RPES4946)
Product Code:RPES4946
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Myelin-Oligodendrocyte Glycoprotein, MOG,BTN6,BTNL11,MOGIG2,NRCLP7
Accession:Q16653
Sequence:Gly30-Gly154
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our Mammalian expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:15.3 kDa
AP Mol Mass:19 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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