Human IL15RA/IL5RA Recombinant Protein (RPES1094)

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SKU:
RPES1094
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human IL15RA/IL5RA Recombinant Protein

Interleukin 15 Receptor alpha (IL-15R?) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15R? chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15R? can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15R? complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and ? heterodimers and enables signaling to cells.

Product Name:Human IL15RA/IL5RA Recombinant Protein (RPES1094)
Product Code:RPES1094
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:CD215, IL15RA, CD215 antigen, IL-15 receptor subunit alpha, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179
Accession:Q13261
Sequence:Ile31-Thr 205
Fusion tag:C-Fc
Activity:Measured by its ability to block human IL-15-induced proliferation of CTLL?2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Ile31-Thr205 is expressed with a Fc tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:45.5 kDa
AP Mol Mass:36-50 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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