Human Hyaluronidase/HYAL1 Recombinant Protein (RPES0861)

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SKU:
RPES0861
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Hyaluronidase/HYAL1 Recombinant Protein

Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

Product Name:Human Hyaluronidase/HYAL1 Recombinant Protein (RPES0861)
Product Code:RPES0861
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1
Accession:Q12794
Sequence:Phe22-Trp435
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:47.2 kDa
AP Mol Mass:52 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, 10%Glycerol, pH7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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