Human Galectin 9/LGALS9 Recombinant Protein (RPES4572)

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SKU:
RPES4572
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Galectin 9/LGALS9 Recombinant Protein

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin ?4β1.

Product Name:Human Galectin 9/LGALS9 Recombinant Protein (RPES4572)
Product Code:RPES4572
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Galectin-9, Gal-9, Ecalectin, Tumor Antigen HOM-HD-21, LGALS9
Accession:Q3B8N1-2
Sequence:Met 1-Thr323
Fusion tag:C-6His
Activity:Immobilized Human Galectin 9-His at 10µg/ml(100 ?l/well) can bind Cynomolgus TIM-3-His(Cat: PKSQ050023). The ED50 of Human Galectin 9-His is 1.75 ug/ml .
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Galectin 9 is produced by our Mammalian expression system and the target gene encoding Met1-Thr323 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:36.9 kDa
AP Mol Mass:49 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS,5% Trehalose,1mM EDTA,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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