Human DCTN6 Recombinant Protein (RPPB3339)

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SKU:
RPPB3339
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
DCTN6
Synonyms:
Dynactin 6
Synonyms:
WS3
Synonyms:
Dynactin Subunit P27
Synonyms:
Protein WS-3
Source:
Escherichia Coli
Uniprot:
O00399
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Description

Product Name:Human DCTN6 Recombinant Protein
Product Code:RPPB3339
Size:20µg
Species:Human
Target:DCTN6
Synonyms:Dynactin 6, WS3, Dynactin Subunit P27, Protein WS-3, P27,Novel RGD-Containing Protein, Dynactin Subunit 6, WS-3, Dynactin subunit 6.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:DCTN6 protein solution (1mg/ml) containing PhosphateBuffered Saline (pH7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAEKTQK SVKIAPGAVV CVESEIRGDV TIGPRTVIHP KARIIAEAGPIVIGEGNLIE EQALIINAYP DNITPDTEDP EPKPMIIGTN NVFEVGCYSQ AMKMGDNNVI ESKAYVGRNVILTSGCIIGA CCNLNTFEVI PENTVIYGAD CLRRVQTERPQPQTLQLDFL MKILPNYHHL KKTMKGSSTP VKN

Dynactin 6, also known as DCTN6 is a member of the dynactin subunits 5/6family. DCTN6 includes an RGD (Arg-Gly-Asp) motif in the N-terminal region,which confers adhesive properties to macromolecular proteins such asfibronectin. DCTN6 has a high degree of sequence resemblance with the mousehomolog, which has been found to participate in mitochondrial biogenesis.Moreover, the precise biological function of DCTN6 is unknown.

DCTN6 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 213 amino acids (1-190 a.a) andhaving a molecular mass of 23.1kDa.DCTN6 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:dynactin 6: contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8p12

Cellular Component: centrosome; cytosol

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport

NCBI Summary:The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. [provided by RefSeq, Jul 2008]
UniProt Code:O00399
NCBI GenInfo Identifier:3024856
NCBI Gene ID:10671
NCBI Accession:O00399.1
UniProt Secondary Accession:O00399,B2RAC1,
UniProt Related Accession:O00399
Molecular Weight:20,747 Da
NCBI Full Name:Dynactin subunit 6
NCBI Synonym Full Names:dynactin subunit 6
NCBI Official Symbol:DCTN6  
NCBI Official Synonym Symbols:WS3; p27; WS-3  
NCBI Protein Information:dynactin subunit 6
UniProt Protein Name:Dynactin subunit 6
UniProt Synonym Protein Names:Dynactin subunit p27; Protein WS-3
UniProt Gene Name:DCTN6  
UniProt Entry Name:DCTN6_HUMAN
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