Human CXCL1 Recombinant Protein (RPES1222)

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SKU:
RPES1222
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human CXCL1 Recombinant Protein

Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.

Product Name:Human CXCL1 Recombinant Protein (RPES1222)
Product Code:RPES1222
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Growth-Regulated Alpha Protein, C-X-C Motif Chemokine 1, GRO-Alpha(1-73), Melanoma Growth Stimulatory Activity, MGSA, Neutrophil-Activating Protein 3, NAP-3, CXCL1, GRO, GRO1, GROA, MGSA, SCYB1
Accession:P09341
Sequence:Ala35-Asn107
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human C-X-C Motif Chemokine 1 is produced by our Mammalian expression system and the target gene encoding Ala35-Asn107 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:8.9 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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