Human CHI3L1/YKL40 Recombinant Protein (RPES3493)

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SKU:
RPES3493
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Human CHI3L1/YKL40 Recombinant Protein

Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.

Product Name:Human CHI3L1/YKL40 Recombinant Protein (RPES3493)
Product Code:RPES3493
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Chitinase-3-Like protein 1, 39 kDa Synovial Protein, Cartilage Glycoprotein 39, CGP-39, GP-39, hCGP-39, YKL-40, CHI3L1,ASRT7,DKFZp686N19119,FLJ38139,GP39,HC-gp39,HCGP-3P,YKL40,YYL-40
Accession:P36222
Sequence:Tyr22-Thr383
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Chitinase-3-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr22-Thr383 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:41.5 kDa
AP Mol Mass:46 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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