Human Calcitonin/CALCA Recombinant Protein (RPES3932)

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SKU:
RPES3932
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Calcitonin/CALCA Recombinant Protein

Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+); opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals; as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

Product Name:Human Calcitonin/CALCA Recombinant Protein (RPES3932)
Product Code:RPES3932
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1
Accession:P01258
Sequence:Tyr58-Asn141
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Calcitonin is produced by our E.coli expression system and the target gene encoding Tyr58-Asn141 is expressed with a 6His tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:10.5 kDa
AP Mol Mass:16 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB;150mM NaCl;50% Glycerol;pH7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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