Human BPHL Recombinant Protein (RPES3647)

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SKU:
RPES3647
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human BPHL Recombinant Protein

BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. BPHL also activates valacyclovir to acyclovir. It may play a role in detoxification processes.

Product Name:Human BPHL Recombinant Protein (RPES3647)
Product Code:RPES3647
Size:20µg
Species:Human
Expressed Host:E.coli
Synonyms:BPH-RP,MCNAA,VACVASE
Accession:Q86WA6-1
Sequence:Ser38-Gln291
Fusion tag:N-His
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding the mature form of human BPHL (Q86WA6-1) (Ser38-Gln291) was expressed with a polyhistide tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:30.7 kDa
AP Mol Mass:31 kDa
Formulation:Lyophilized from sterile 20mM Tris, 50mM NaCl, 10% glycerol, pH 8.0
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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