Human BNIP3/NIP3 Recombinant Protein (RPES3524)

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SKU:
RPES3524
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Human BNIP3/NIP3 Recombinant Protein

BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process.

Product Name:Human BNIP3/NIP3 Recombinant Protein (RPES3524)
Product Code:RPES3524
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3, BNIP3, NIP3
Accession:Q12983
Sequence:Met 1-Leu166
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Adenovirus E1B 19 kDa Protein-Interacting Protein 3 is produced by our E.coli expression system and the target gene encoding Met1-Leu166 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:20.6 kDa
AP Mol Mass:28 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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